Flu? Malaria? Disease forecasters look to the sky






NEW YORK (AP) — Only a 10 percent chance of showers today, but a 70 percent chance of flu next month.


That’s the kind of forecasting health scientists are trying to move toward, as they increasingly include weather data in their attempts to predict disease outbreaks.






In one recent study, two scientists reported they could predict — more than seven weeks in advance — when flu season was going to peak in New York City. Theirs was just the latest in a growing wave of computer models that factor in rainfall, temperature or other weather conditions to forecast disease.


Health officials are excited by this kind of work and the idea that it could be used to fine-tune vaccination campaigns or other disease prevention efforts.


At the same time, experts note that outbreaks are influenced as much, or more, by human behavior and other factors as by the weather. Some argue weather-based outbreak predictions still have a long way to go. And when government health officials warned in early December that flu season seemed to be off to an early start, they said there was no evidence it was driven by the weather.


This disease-forecasting concept is not new: Scientists have been working on mathematical models to predict outbreaks for decades and have long factored in the weather. They have known, for example, that temperature and rainfall affect the breeding of mosquitoes that carry malaria, West Nile virus and other dangerous diseases.


Recent improvements in weather-tracking have helped, including satellite technology and more sophisticated computer data processing.


As a result, “in the last five years or so, there’s been quite an improvement and acceleration” in weather-focused disease modeling, said Ira Longini, a University of Florida biostatistician who’s worked on outbreak prediction projects.


Some models have been labeled successes.


In the United States, researchers at Johns Hopkins University and the University of New Mexico tried to predict outbreaks of hantavirus in the late 1990s. They used rain and snow data and other information to study patterns of plant growth that attract rodents. People catch the disease from the droppings of infected rodents.


“We predicted what would happen later that year,” said Gregory Glass, a Johns Hopkins researcher who worked on the project.


More recently, in east Africa, satellites have been used to predict rainfall by measuring sea-surface temperatures and cloud density. That’s been used to generate “risk maps” for Rift Valley fever — a virus that spreads from animals to people and in severe cases can cause blindness or death. Researchers have said the system in some cases has given two to six weeks advance warning.


Last year, other researchers using satellite data in east Africa said they found that a small change in average temperature was a warning sign cholera cases would double within four months.


“We are getting very close to developing a viable forecasting system” against cholera that can help health officials in African countries ramp up emergency vaccinations and other efforts, said a statement by one of the authors, Rita Reyburn of the International Vaccine Institute in Seoul, South Korea.


Some diseases are hard to forecast, such as West Nile virus. Last year, the U.S. suffered one of its worst years since the virus arrived in 1999. There were more than 2,600 serious illnesses and nearly 240 deaths.


Officials said the mild winter, early spring and very hot summer helped spur mosquito breeding and the spread of the virus. But the danger wasn’t spread uniformly. In Texas, the Dallas area was particularly hard-hit, while other places, including some with similar weather patterns and the same type of mosquitoes, were not as affected.


“Why Dallas, and not areas with similar ecological conditions? We don’t really know,” said Roger Nasci of the Centers for Disease Control and Prevention. He is chief of the CDC branch that tracks insect-borne viruses.


Some think flu lends itself to outbreak forecasting — there’s already a predictability to the annual winter flu season. But that’s been tricky, too.


Seasonal flu reports come from doctors’ offices, but those show the disease when it’s already spreading. Some researchers have studied tweets on Twitter and searches on Google, but their work has offered a jump of only a week or two on traditional methods.


In the study of New York City flu cases published last month in the Proceedings of the National Academy of Sciences, the authors said they could forecast, by up to seven weeks, the peak of flu season.


They designed a model based on weather and flu data from past years, 2003-09. In part, their design was based on earlier studies that found flu virus spreads better when the air is dry and turns colder. They made calculations based on humidity readings and on Google Flu Trends, which tracks how many people are searching each day for information on flu-related topics (often because they’re beginning to feel ill).


Using that model, they hope to try real-time predictions as early as next year, said Jeffrey Shaman of Columbia University, who led the work.


“It’s certainly exciting,” said Lyn Finelli, the CDC’s flu surveillance chief. She said the CDC supports Shaman’s work, but agency officials are eager to see follow-up studies showing the model can predict flu trends in places different from New York, like Miami.


Despite the optimism by some, Dr. Edward Ryan, a Harvard University professor of immunology and infectious diseases, is cautious about weather-based prediction models. “I’m not sure any of them are ready for prime time,” he said.


Health News Headlines – Yahoo! News





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Markets rally on US fiscal deal







Continue reading the main story






Global stock markets have rallied after a short-term deal to stave off the US “fiscal cliff” was reached.


The Dow Jones gained 1.8% at the open on Wall Street, while European shares were up by more than 2% for the day.


Failure to agree a deal would have triggered spending cuts and tax rises worth $ 600bn (£370bn), expected to throw the US back into recession.


However, the deal has only postponed by two months negotiations over spending cuts and the government debt ceiling.


Just before the New Year, the US Treasury Secretary Tim Geithner indicated that the federal government would run up against the debt ceiling – a legal cap on its total borrowing set by Congress – by the end of February.


The fiscal cliff deal does not include an increase in the debt ceiling. It also postpones by two months steep automatic spending cuts to federal government spending on things like defence and education.


The fiscal cliff measures – immediate tax rises worth $ 536bn, as well as spending cuts of $ 109bn from benefit payments and domestic and military programmes – were due to come into effect automatically at midnight on Monday.


Tax rises


The deal has averted most of these measures, including:


Continue reading the main story

Start Quote



This week’s deal lifts the risk of an accidental recession – at least for a while”



End Quote



  • making permanent tax cuts dating back to George W Bush’s presidency, for individuals earning less than $ 400,000

  • postponing the $ 65bn of automatic spending cuts for two months

  • keeping benefits available for the long-term unemployed, worth $ 26bn, for another year

  • postponing for another year an $ 11bn cut in Medicare payments

However, the deal did also allow some tax rises to go ahead, namely:


  • the expiry of a payroll tax holiday, expected to raise $ 95bn in additional annual revenue

  • allowing the Bush-era income tax cuts for individuals earning over $ 400,000 to come to an end, with the top rate increasing from 35% to 40%

  • higher taxes on dividend income, capital gains and inheritance for these same top earners

  • phasing out certain income tax deductions for individuals earning more than $ 200,000

The increase in payroll taxes is likely to be the most significant of these measures, in terms of how much it raises in revenue for the government, the number of taxpayers affected, and its impact on the economy.


Payroll tax is paid by all employees. The tax holiday – which cut the rate from 6.2% to 4.2% – was introduced by President Barack Obama three years ago to help stimulate the lethargic economy by putting more money in the pockets of ordinary American workers, who were most likely to go out and spend it.


Continue reading the main story

Start Quote



The battle [over spending cuts] has just been shoved two months down the road”



End Quote



Economists suggest that its expiry is likely to have the biggest impact on spending – particularly consumer spending – in the US.


Jan Hatzius, chief economist at Goldman Sachs, has said it would reduce US economy growth by 0.6%.


‘Disappointment’


The deal has postponed the hardest decisions that Republican and Democratic politicians must still reach agreement on – over spending cuts and the debt ceiling.


Both issues will need to be addressed at the end of February, with Republicans likely to demand deep cuts, particularly to entitlement programmes such as social security, in return for an increase in the legal cap on government borrowing.


President Obama’s Democrats would prefer to reduce the government’s deficit via further tax rises.


“In the most immediate sense, they took their feet of the cliff, but once again they have taken the hard work and pushed it down the street,” said Daniel Costello, a US economics commentator.


Continue reading the main story

Fiscal cliff explained


  • On 1 January 2013, tax increases and huge spending cuts were due to come into force – the so-called fiscal cliff

  • The deadline was put in place in 2011 to force the president and Congress to agree ways to save money over the next 10 years

  • The fear was that raising taxes while massively cutting spending would have huge impact on households and businesses

  • Experts believed it could have pushed the US into recession, and had a global impact on growth

  • A deal has been reached delaying some of the tax rises and all of the spending cuts by at least two months


“It’s a huge disappointment. The Republicans deeply wanted spending cuts. Their long-term goal is to finally start chipping away at some of the entitlement spending [on welfare payments] that is just getting out of control.”


Entitlement payments are expected to rise sharply in the coming decades as the post-World War II baby-boom generation retires and enters old age, entailing more government-funded medical care.


“Two-thirds of all federal spending comes from entitlement spending – that means when you wake up in the morning, two-thirds of the money is already spent. By 2020, that goes up to 90%.”


When President Obama last faced off against the largely Republican-controlled Congress over the debt ceiling in 2011, negotiations went to the wire before agreement was reached to increase the ceiling from $ 14.3tn to $ 14.7tn.


Markets fell sharply at the time on fears that, legally barred from borrowing any more, the government might be forced to default on some of its payment obligations, with unknown but potentially significant legal consequences.


The political wrangling also prompted ratings agency Standard and Poor’s to deprive the US of its top AAA credit rating.


Temporary lift


Despite the deal’s shortcomings, markets took cheer from the fact that agreement had been reached on how to postpone and moderate the process of bringing the government’s overspending back under control.




Richard Hunter, Hargreaves Lansdown: “This points the market in the right direction”



The FTSE 100 index rose 145 points to 6,043 points, the first time it has been above the 6,000 level in 17 months, with mining shares leading the way.


The UK market was also boosted by a survey of production and new orders in the manufacturing sector, which showed activity at a 15-month high in December.


Shares worldwide had been hurt in November and December by fears that the US would not be able to reach any kind of agreement and would go off the cliff.


Analysts said the relief would not last.


Mike McCudden, head of derivatives at stockbroker Interactive Investor said: “There will no doubt be a few more twists and turns in the days ahead… but for now, investors have the concrete news they were hoping for.”


Joe Rundle, head of trading at ETX Capital, said: “Today’s bullish tone may continue as we head toward the weekend. but the euphoria will most certainly evaporate, as the deal voted through does not include raising the debt ceiling and longer-term budget cuts.


“It’s only a matter of time before market participants lose their buzz as US lawmakers will have to reconvene to address the remainder of unresolved issues.”


BBC News – Business





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Israeli-Palestinian clashes erupt in West Bank






TAMOUN, West Bank (AP) — An arrest raid by undercover Israeli soldiers disguised as vegetable vendors ignited rare clashes in the northern West Bank on Tuesday, residents said, leaving at 10 Palestinians wounded.


Israeli army raids into Palestinian areas to seize activists and militants are fairly common. The raids are normally coordinated with Palestinian security forces, and suspects are usually apprehended without violence.






The clashes began early Tuesday after Israeli forces disguised as merchants in a vegetable truck arrested one man. Regular army forces then entered the town, prompting youths to hurl rocks to try to prevent more arrests.


Israeli forces fired tear gas, rubber bullets and live ammunition as youths set tires and bins on fire to block the passage of military vehicles. In several hours of clashes, dozens of masked youths hid behind makeshift barriers, hurling rocks and firebombs at soldiers.


Faris Bisharat, a resident of Tamoun, said 10 men were wounded, some by live fire. Bisharat said the wanted men belong to Islamic Jihad, a violent group sworn to Israel’s destruction. It wasn’t clear how many men Israeli forces sought to arrest. There were no immediate details on how seriously the 10 were hurt.


The Israeli military said it arrested a “terrorist affiliated with the Islamic Jihad terror group.” It said two soldiers were injured during the raid.


The fighting, which broke out in several parts of the town of some 8,000 people, were a rare, angry response. It was also unusual for Israeli forces to use live fire toward Palestinian demonstrators. Israel says it uses live fire only in extremely dangerous situations.


Middle East News Headlines – Yahoo! News





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Apple testing new iPhone, iOS 7: report






(Reuters) – Apple Inc has started testing a new iPhone and the next version of its iOS software, news website The Next Web reported.


Apple shares were up 2.6 percent at $ 546.06 in premarket trading. The stock closed at $ 532.17 on the Nasdaq on Monday.






Application developers have found in their app usage logs references to a new iPhone identifier, iPhone 6.1, running iOS 7 operating system, the website reported. (http://r.reuters.com/fyd94t)


Apple‘s iPhone 5 bears the identifiers “iPhone 5.1″ and “iPhone 5.2″ and is powered by iOS 6 operating system.


Developer logs show that the app requests originate from an internet address on Apple’s Cupertino campus, suggesting that Apple engineers are testing compatibility for some of the popular apps, the website said.


“Although OS and device data can be faked, the unique IP footprint leading back to Apple’s Cupertino campus leads us to believe this is not one of those attempts,” the website said.


Apple launched iPhone 5 in September and it has been reported that the new iPhone will be released in the middle of 2013.


(Reporting by Supantha Mukherjee in Bangalore)


Tech News Headlines – Yahoo! News





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Jon Stewart to host Grammy’s MusiCares tribute






LOS ANGELES (AP) — Jon Stewart is hosting the MusiCares salute to Bruce Springsteen.


The Recording Academy also announced Wednesday that Elton John, Neil Young, Mumford & Sons, Sting, Mavis Staples and Kenny Chesney will be among more than a dozen performers who will help pay tribute to Springsteen during the Feb. 8 benefit concert, held in Los Angeles two days before the Grammy Awards.






Springsteen is MusiCare’s person of the year, an award given to a performer who is notable both artistically and philanthropically. The sold-out concert will benefit MusiCare’s emergency financial assistance and addiction recovery programs.


Other performers scheduled to appear include Juanes, Tim McGraw and Faith Hill, Jackson Browne and Alabama Shakes.


Stewart is the host of Comedy Central’s “The Daily Show With Jon Stewart.”


___


Online:


http://grammy.com


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Women Lose Half Their Weight: How They Did It






At 25 years old and 288 pounds, Ashley Donahoo was depressed.


“I was unhappy with my job, I was unhappy with the direction my life was going, and I had a hard time enjoying the little things that my kids wanted to do,” the 27-year-old mother of two from Pace, Fla., said. “My health was failing. My doctor told me that he didn’t think I was going to make it to 30 if I kept on [this way]. … It kept getting worse and worse.”






Donahoo was concerned, but it was her faithful husband, David, who pushed her on a path to health, starting with a walk around the block.


“His heart was breaking for me,” she said. “And he saw how unhappy I was, and he came to me and said, ‘We’re going to go for a walk.’  And I was, like, ‘No, we’re not.’”


Her husband won that battle, and on the walk, she started thinking about her own choices and future.


“The realization hit me that I made this choice.  I made this choice to get where I am right now.  So I’m going to start making a different choice,” she said.   ”I put my health and myself on back burner, and I think … it had all caught up to me.”


Jumpstart Your Weight Loss: CLICK HERE to Ask a Celebrity Trainer a Question!


Like Donahoo, Caroline Jhingory reached a similar eye-opening realization about her weight.


“I looked in the mirror one day and just realized I didn’t recognize the person that was staring back at me,” said Jhingory, 32, of Washington, D.C.


Jhingory’s struggles with her weight began early. At age 8, she weighed 120 pounds. Taunted by her peers, Jhingory was enrolled in a medical weight loss program, but it didn’t work because she would sneak junk food like candy bars.


“I found a way to be a food hustler and get whatever food I wanted,” she said. “Not only did I spend two decades of my life morbidly obese. I spent two decades of my life being taunted and teased in every environment. I never went to prom. I never had dates. I couldn’t ride a roller coaster because the safety bar wouldn’t go over my stomach.”


Jhingory remained heavy until college, when she tipped the scales at 303 pounds and started feeling self-conscious in her new environment.


“I felt like I had a moment when all these difficult experiences were a huge pause button on my life. I finally said to myself, ‘I’m tired of this. I want to have a normal life.’”


Jhingory started walking everywhere. Then, she took up a daily cardio regimen to shed the weight, and she rid her pantry of tempting snack foods she once binged on. Now 149 pounds, she has reclaimed her shape and kept off the weight.


Jhingory’s amazing transformation, along with Donahoo’s and other weight-loss success stories, were spotlighted in the “Half Their Size” feature in the latest issue of People magazine.


RELATED: Is Being Overweight Really Bad For You?


Donahoo cut out the late-night binges that brought her down and, thanks to her strong support system, lost 137 pounds. She credited her weight loss success to tracking her food and exercise on livestrong.com and running. She has run two 5Ks.


Leah Fernandez of Atlanta found herself at 251 pounds after two pregnancies. The baby weight stuck and she tended to eat emotionally.


“I wanted the food,” she said. “It made me feel good, and so I ate it.”


But it was the motivation to be there for her children that helped her turn it all around.


“Thinking about going out to the park with my kids felt like work to me, you know?  And at some point I realized that’s ridiculous. Not only am I cheating myself but I’m cheating my kids of me,” she said.


Fernandez turned to Jenny Craig in March 2011 and hasn’t looked back. Since then, she has lost half her weight by staying active with her kids and incorporating walking into her lifestyle.


“I’m getting my groove back.  Leah’s getting her groove back,” she said.


RELATED: Apps to Help With Weight-Loss Resolutions


RELATED: 329 Pound-Weight-Loss Trio Share Their Secrets


READ MORE: 138 Pound Weight Loss Changes Woman’s Life


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UK assumes presidency of G8 group







The UK is assuming its year-long presidency of the G8 group of nations.






The presidency – which rotates through the G8 members – means it will host the annual leaders’ summit and choose the global priorities that are discussed.


June’s summit is to be held at Lough Erne, in County Fermanagh, while topics discussed will include tax havens.


The G8 is made up countries who have, historically, been the richest in the world – France, the US, Russia, Japan, Germany, Italy, Canada and the UK.


As prime minister of the presidency holding nation, David Cameron has said he wants to focus on combating trade protectionism, cracking down on tax havens and promoting greater government transparency.


These topics will be discussed in ministerial meetings ahead of the summit along with urgent issues like the crisis in Syria.


Although G8 summits are renowned for fine communiques, the group increasingly suffers from a credibility problem – some of the world’s largest economies like China, India and Brazil are not members, says BBC world affairs correspondent Emily Buchanan.


Our correspondent also adds that organisers will at least be hoping the June summit will be trouble-free.


The last time the UK was the host in 2005, in Gleneagles, more than 200,000 people marched against world poverty.


The proceedings were then overshadowed by the 7/7 bus and underground bombings in London.


Mr Cameron announced in November that the G8 summit would be held at the Lough Erne golf resort near Enniskillen.


It is the first time an event of this size has been held in Northern Ireland.


Speaking at the time, the prime minister said: “I want the world to see just what a fantastic place Northern Ireland is – a great place for business, a great place for investment, a place with an incredibly educated and trained workforce ready to work for international business.


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Relive the Paralympics’ Most Inspiring Moment of the Year






Back in July, we covered how social media would be critical to the success of the 2012 Paralympic Games. The Paralympics ended in September, but the International Paralympic Committee is still using the web to shine a light on unheralded athletes and tell stories of remarkable inspiration.


[More from Mashable: Watch the Scariest Skiing Lesson of All Time]






The committee revealed its top moment of 2012 in a video posted to YouTube on Sunday. It profiles Italian cyclist Alex Zanardi winning gold in London after losing his legs in an auto racing accident in 2001. The image of a triumphant Zanardi lifting his hand-cycling tricycle above his head with one arm post-race is nothing short of astounding.


[More from Mashable: NBA Star’s Kick to the Groin Sparks Online Debate]


For a longer look at Zanardi’s amazing achievement and to relive one of 2012′s sweetest sports moments, watch the full video above.


BONUS: 2012′s best sports social media moments


1. Devin McCourty Tweets While Playing in the Super Bowl (Sort of)


As New England Patriot Devin McCourty took on the New York Giants in Super Bowl XLVI, his followers were still able to receive real-time updates from his social feeds. But he wasn’t sneaking tweets between plays or during timeouts. Devin and twin brother Jason, who plays for the Tennessee Titans, share their Twitter and Facebook accounts. The Super Bowl showcased one of the more creative approaches to social media in the sports world.


Image courtesy of Devin and Jason McCourty’s Instagram.


Click here to view this gallery.


Thumbnail image credit Getty Images/AFP/Leon Neal


This story originally published on Mashable here.


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ESPN’s Hannah Storm returns 3 weeks after accident






NEW YORK (AP) — ESPN anchor Hannah Storm returns to the air New Year’s Day, exactly three weeks after she was seriously burned in a propane gas grill accident at her home.


Storm suffered second-degree burns on her chest and hands, and first-degree burns to her face and neck. She lost her eyebrows and eyelashes, and roughly half her hair.






Storm will host ABC’s telecast of the 2013 Rose Parade on Tuesday. Her left hand will be bandaged and she said viewers might notice a difference in her hair texture where extensions have been added.


“I’m a little nervous about things I used to take for granted,” she said by phone this weekend from Pasadena, Calif. “Little things like putting on makeup and even turning pages on my script.”


The award-winning sportscaster and producer was preparing dinner outside her home in Connecticut on the night of Dec. 11 when she noticed the flame on the grill had gone out. She turned off the gas and when she reignited it “there was an explosion and a wall of fire came at me.”


“It was like you see in a movie, it happened in a split-second,” she said. “A neighbor said he thought a tree had fallen through the roof, it was that loud. It blew the doors off the grill.”


With her left hand, she tore off her burning shirt. She tried to use another part of her shirt to extinguish the flames that engulfed her head and chest, while yelling for help. Her 15-year-old daughter, Hannah, called 911 and a computer technician who was working in the house grabbed some ice as Storm tried to cool the burns.


Soon, police and rescue teams arrived at the house. Storm’s husband, NBC sportscaster Dan Hicks, also had returned home with another of the couple’s three daughters. As her mother was being treated, the younger Hannah calmly said something that, days later, her mom could laugh about.


“OK, Mommy, I’m going to do my homework now,” she said.


Storm was taken by ambulance to the Trauma and Burn Center at Westchester Medical Center and was treated for 24 hours.


“I didn’t see my face until the next day and you wonder how it’s going to look,” she said. “I was pretty shocked. But my overarching thought was I’ve covered events with military members who have been through a lot worse than me, and they’ve come through. I kept thinking, ‘I can do this. I’m fortunate.’”


Other than going to Christmas Eve Mass, Storm hadn’t been outside until her trip to California. ESPN reworked its anchor schedule while she was recovering, and NBC and the Golf Channel rearranged their staffing while Hicks attended to his wife.


Storm is set to host her fifth Rose Parade, with some changes. She’s left-handed, and taking notes is almost impossible. Dressing and showering are challenges, too.


Storm said that long before her accident, she’d been inspired by Iraq War veteran, actor and “Dancing With the Stars” winner J.R. Martinez, the grand marshal at last year’s parade. He was severely burned in a land mine accident while serving overseas.


One attraction of this year’s parade that she was eager to see — the Nurses’ Float, and she hoped to use that moment on air to thank everyone who had taken care of her.


Storm wants to anchor “SportsCenter” in Bristol, Conn., next Sunday. After that, the Notre Dame alum is ready to go in person to watch the No. 1 Irish play Alabama in the national championship game at Miami. She said the school reached out after hearing about her injuries and had been very supportive.


“More than anything, I feel gratitude,” she said. “Something like this really makes you appreciate everything you have, even the chance to wake up on New Year’s Day and do your job.”


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Could Trip to Mars Cause Alzheimer’s?






Space travel has always been portrayed as risky — no air or water, extreme temperatures — a place where even a small miscalculation can be fatal. It can also be hazardous to your brain health, particularly on a three-year-long mission to Mars, according to a study published this week in the scientific journal PLOS ONE.


The eight-year long study, conducted at the NASA Space Radiation Laboratory at Brookhaven National Laboratory on New York’s Long Island, found that the cosmic radiation on such a mission could accelerate the onset of Alzheimer’s disease.






NASA is working on sending astronauts to a passing asteroid in the 2020s, and talks of a trip to Mars in the 2030s. It would take three years, with current technology, to get there and back. Current spacecraft are not heavily shielded from the cosmic radiation crew members would encounter beyond Earth’s protective magnetic field.


Researchers used mice that were genetically engineered to be predisposed to Alzheimer’s disease. They exposed them to cosmic radiation that was simulated in the lab.


“Galactic cosmic radiation poses a significant threat to future astronauts,” said Dr. M. Kerry O’Banion, senior author and professor of neurobiology and anatomy at the University of Rochester Medical Center.


The study team wanted to see if radiation had the potential to accelerate Alzheimer’s in those who were genetically vulnerable. Mouse models have been used extensively in this type of research and the rate at which they develop the disease is well understood.


Scientists have long worried about the potential dangers of working and living in deep space. Cosmic radiation beyond low Earth orbit, researchers say, could lead to cancer, cardiovascular disease, even cataracts.


Radiation exposure can cause acute effects such as nausea, vomiting, fatigue, skin injury and changes to white blood cell counts and the immune system, according to the National Space Biomedical Research Institute. Longer-term radiation effects include damage to the eyes, gastrointestinal system, lungs and central nervous system.


On Earth, humans are protected by the planet’s atmosphere and magnetic field. Crew members on the International Space Station, at an altitude of 200 miles, are still within the magnetic sheath that surrounds us. The 24 Apollo astronauts who flew to the moon between 1969 and 1972 were not protected, but the longest missions lasted less than two weeks.


Once out of low orbit, astronauts are exposed to showers of different radioactive particles. Though engineers say they can protect themselves from the radiation associated with solar flares, so far, they cannot block other forms of cosmic radiation.


The longer astronauts are in deep space, the greater the exposure to this low-level radiation.


This is the first such study to explore effects of radiation on the nervous system, a phenomenon known as neurodegeneration, according to the authors.


“The possibility that radiation exposure in space may give rise to health problems such as cancer has long been recognized,” said O’Banion. “However, this study shows for the first time that exposure to radiation levels equivalent to a mission to Mars could produce cognitive problems and speed up changes in the brain that are associated with Alzheimer’s disease.”


O’Banion has spent the last 20 years studying Alzheimer’s disease.


He and his fellow researchers studied a form of radiation from so-called high-mass, high-charged particles, which come in various forms and fly through space at high speeds. Some come from distant stars that have exploded.


At Brookhaven, where a portion of the research was conducted, particle accelerators were able to recreate some of the radioactive particles found in space.


“It is extremely difficult from an engineering perspective to effectively shield against them,” said O’Banion. “One would have to essentially wrap a spacecraft in a six-foot block of lead or concrete.”


For the study, researchers used mice that had been engineered to have two human gene mutations associated with familial Alzheimer’s.


“Essentially, they were healthy mice with nasty genes,” said O’Banion. Under natural conditions, mice do not get the disease.


The mice were exposed to the radiation for several minutes. Six months later, researchers evaluated the exposure to see if it had any effect.


“A minute or two [of exposure] is like three years in human life,” O’Banion said. “It’s apples and oranges, a very different kind of exposure, but the total dose is equivalent to what an astronaut would receive [on a three-year Mars mission].”


Cosmic radiation is unlike anything on earth, according to O’Banion, similar only to what might be experienced in a nuclear accident.


“The big problem NASA faces is that shielding is not effective, and a spacecraft is not bulky enough to protect them over long periods of travel,” said O’Banion. “At least not now. In scenarios I have heard of sending people to Mars, they would then build an underground shelter on a long-term mission in order to protect them from radiation.”


While the research does not solve the problem of radiation in space or explain why humans develop Alzheimer’s disease, it is important, according to O’Banion.


“My own bias is this,” he said. “It’s just another example of how the environment can influence diseases. The mice had a genetic predisposition and you have added an environmental injury — an insult to their system. And now they show exacerbation of the disease.”


There may even be parallels with the development of the disease after brain injuries in football players, he said.


Jeff Chancellor, a scientist in radiation physics at the National Space Biomedical Research Institute, said the Rochester team’s study is solid.


“I know most of the authors and they are very well respected, and I have full confidence in their results,” he said. . “The main benefit of their research is being able to further enhance the field and perhaps provide justification for more research.”


“Any time you identify a mechanism for how a disease or a condition is induced, you further the ability to mitigate it,” he said. “It provides more tools for the researchers and for M.D.s … There are great benefits to all these studies.”


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